Drugs for Parkinson's -- Side Effects
After examining 2.7 million reports of drug reactions submitted to an FDA database between 2003 and 2012, researchers published a study in JAMA Internal Medicine that independently corroborated that a disproportionate number of people living with PD have reported impulse control disorders.
The study results reflect that although dopamine medications (such as Mirapex, Requip and Neupro) are essential to treating Parkinson’s Disease (PD), the challenge is to find a balance between high and low levels of dopamine. Long-term exposure to dopamine medications, especially dopamine agonists (DAs), can cause a hypersensitivity to dopamine. The body overreacts, and this in turn can lead to an impulse control disorder (ICD) — a group of behaviors that includes gambling, uncontrollable shopping, compulsive eating, a sudden obsession with sex, punding (stereotypic, complex, and repetitive behavior involving meaningless activities) — as well as a related disorder, excessive daytime sleepiness.