Brain stimulation reduces suicidal thinking in people with hard-to-treat depression: Findings indicate promising directions to prevent suicide across mental illnesses -- ScienceDaily
A non-invasive form of brain stimulation, rTMS directs magnetic pulses at a targeted area of the brain. In these studies, rTMS was applied to the dorsolateral prefrontal cortex, an area in the frontal lobes, five times a week for either three or six weeks. Participants were randomized to receive rTMS in one of three ways: to both the right and left frontal lobes (bilateral rTMS), the left frontal lobe only (unilateral rTMS) or, as a comparison group, sham rTMS, which is similar to a placebo.
Bilateral rTMS showed the biggest effect, and outperformed both other types. Forty per cent of people who received bilateral rTMS reported that they no longer experienced suicidal thoughts by the study end. By comparison, 27 per cent of those who received unilateral rTMS, and 19 per cent of those who received sham rTMS no longer experienced suicidal thoughts. Bilateral rTMS was also the most effective at preventing the development of suicidal thoughts in people who were not experiencing suicidal thinking at the start of the study.