Sensor created to detect dopamine, brain disorders, in seconds -- ScienceDaily
Current methods to detect dopamine are time consuming, require rigorous sample preparation, including blood-plasma separation, as well as specialized laboratory equipment. With this device, however, a few drops of blood on a palm-sized, rectangular chip is all that is needed.
"A neurotransmitter like dopamine is an important chemical to monitor for our overall well-being so we can help screen out neural disorders like Parkinson's disease, various brain cancers, and monitor mental health," said Debashis Chanda, an associate professor in UCF's NanoScience Technology Center and the study's principle investigator. "We need to monitor dopamine so that we can adjust our medical doses to help address those problems."
Plasma is separated from the blood within the chip. Cerium oxide nanoparticles, which coat the sensor surface, selectively capture dopamine at microscopic levels from the plasma. The capture of dopamine molecules subsequently changes how light is reflected from the sensor and creates an optical readout indicating the level of dopamine.