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Why being left-handed matters for mental health treatment -- ScienceDaily

Since the 1970s, hundreds of studies have suggested that each hemisphere of the brain is home to a specific type of emotion. Emotions linked to approaching and engaging with the world -- like happiness, pride and anger -- lives in the left side of the brain, while emotions associated with avoidance -- like disgust and fear -- are housed in the right. But those studies were done almost exclusively on right-handed people. That simple fact has given us a skewed understanding of how emotion works in the brain, according to Daniel Casasanto, associate professor of human development and psychology at Cornell University. That longstanding model is, in fact, reversed in left-handed people, whose emotions like alertness and determination are housed in the right side of their brains, Casasanto suggests in a new study. Even more radical: The location of a person's neural systems for emotion depends on whether they are left-handed, right-handed or somewhere in between, the research shows. The study, "Approach motivation in human cerebral cortex," is published in Philosophical Transactions of the Royal Society B: Biological Sciences. According to the new theory, called the "sword and shield hypothesis," the way we perform actions with our hands determines how emotions are organized in our brains. Sword fighters of old would wield their swords in their dominant hand to attack the enemy -- an approach action -- and raise their shields with their non-dominant hand to fend off attack -- an avoidance action

Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial - The Lancet

In patients with treatment-resistant depression, iTBS was non-inferior to 10 Hz rTMS for the treatment of depression. Both treatments had low numbers of dropouts and similar side-effects, safety, and tolerability profiles. By use of iTBS, the number of patients treated per day with current rTMS devices can be increased several times without compromising clinical effectiveness.

How Dopamine Neurons Contribute to Memory Formation in Humans - Neuroscience News

“What we discovered was that a subset of the dopaminergic neurons responded only when an image was novel, but not when it was familiar. In other words, it indicated if the image was new, but not if something was familiar,” said Jan Kaminski, PhD, first author of the study and a project scientist at Cedars-Sinai. “This is an important new scientific discovery, because it has so far remained unclear how the dopaminergic system contributes to episodic memory formation.”

What Went Wrong In The First-Ever Clinical Trial Of Deep Brain Stimulation For Depression? - Digg

Finally, Mayberg has long offered her patients comprehensive, personally tailored programs of psychiatric and social-service support to help them rebuild their lives. After years of deep depression, most patients' lives, relationships and ways of thinking have been entrenched in illness and disability long and deeply enough that surgery alone was unlikely to make them whole. Like a patient with a knee repair, says Mayberg, "they need rehab to get well again." So her team helps them get psychotherapy, occupational or physical therapy to rebuild skills or physical health, and other assistance to connect them to needed social services.