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Stress and hippocampus

Research in the neurological literature for years has shown changes in the hippocampus when one has experienced long stress – so a release of hormones such as cortisol actually causes damage to the hippocampus. But as it turns out, it may be that damage to the hippocampus also regulates one’s stress response – and that could contribute to the onset of depression. Again, it’s another one of these vicious cycles. We have a list of 100 potentially stressful events – divorce, moving house, losing loved ones, etc. We found that our group of depressed individuals had not experienced more stressful events in their lives – but they had experienced them as more stressful.

Recovery Is All in Your Head | Outside Online

“Interfering with the natural stress response, particularly by prolonging it, is maladaptive,” says Kiely. “The brain and body will only dedicate resources to rebuilding if it doesn’t feel an emergency is around the corner.” In other words, rushing to work and cranking on a deadline report after a challenging morning workout may seriously mitigate positive physical gains.